Hydrophobic and hydrophilic interactions in countercurrent chromatography
作者: Lihong ZhangShihua Wu
作者单位: 1Research Center of Siyuan Natural Pharmacy and Biotoxicology, College of Life Sciences, Zhejiang University, Hangzhou 310058, PR China
刊名: Journal of Chromatography A, 2020, Vol.1611
来源数据库: Elsevier Journal
DOI: 10.1016/j.chroma.2019.460576
关键词: Countercurrent chromatographyHydrophobic interactionsHydrophilic interactionsAdditivesIonic liquidsSolvent systems selection
原始语种摘要: Abstract(#br)Countercurrent chromatography (or counter-current chromatography, CCC) is a unique support-free liquid-liquid partition chromatography. Since it was invented by Y. Ito in 1960s, CCC has been widely accepted and applied as popular separation and purification technique for natural and synthetic complex. However, up to date there is little study to address on hydrophobic and hydrophilic interactions in CCC process, although hydrophobic interaction chromatography (HIC) and hydrophilic interaction chromatography (or hydrophilic interaction liquid chromatography, HILIC) as solid-support chromatographic techniques are widely applied at different stages of downstream processing. In fact, hydrophobic and hydrophilic interactions might be more popular in CCC separation than that in the...
全文获取路径: Elsevier  (合作)
影响因子:4.612 (2012)

  • hydrophilic 亲水的
  • chromatography 色层分离法
  • hydrophobic 疏水的
  • liquid 液体
  • interaction 相互酌
  • countercurrent 逆流
  • phase 相位
  • separation 分选
  • CCC Carrier Current Communication
  • systems 系统科学与软件