Post-transplant obesity impacts long-term survival after liver transplantation
移植后肥胖影响肝移植术后长期生存
作者: Jeffrey van SonSuzanne P. StamAntonio W. Gomes-NetoMaryse C.J. OstéHans BlokzijlAad P. van den BergRobert J. PorteStephan J.L. BakkerVincent E. de Meijer
作者单位: 1Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
2Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
3Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
刊名: Metabolism, 2020, Vol.106
来源数据库: Elsevier Journal
DOI: 10.1016/j.metabol.2020.154204
关键词: Liver transplantationBody mass indexLong-termSurvivalObesity
英文摘要: Abstract(#br)Background(#br)Short-term survival after orthotopic liver transplantation (OLT) has improved over the past decades, but long-term survival remains impaired. The effects of obesity on long-term survival after OLT are controversial. Because pre-transplant body mass index (BMI) can be confounded by ascites, we hypothesized that post-transplant BMI at 1 year could predict long-term survival.(#br)Methods(#br)A post-hoc analysis was performed of an observational cohort study consisting of adult recipients of a first OLT between 1993 and 2010. Baseline BMI was measured at 1-year post-transplantation to represent a stable condition. Recipients were stratified into normal weight (BMI < 25 kg/m 2 ), overweight (25 ≤ BMI ≤ 30 kg/m 2 ), and obese (BMI > 30 kg/m 2 ). Kaplan-Meier survival...
全文获取路径: Elsevier  (合作)
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影响因子:3.096 (2012)

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关键词翻译
关键词翻译
  • transplant 移植体
  • survival 生存
  • liver 
  • obesity 肥胖
  • after 在之后
  • index 指标