The role of Astakine in Scylla paramamosain against Vibrio alginolyticus and white spot syndrome virus infection
作者: Jing WangWenjing HongFei Zhu
作者单位: 1Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Animal Science and Technology, College of Veterinary Medicine, Zhejiang Agriculture and Forestry University, Hangzhou, 311300, China
刊名: Fish and Shellfish Immunology, 2020, Vol.98 , pp.236-244
来源数据库: Elsevier Journal
DOI: 10.1016/j.fsi.2020.01.024
关键词: Scylla paramamosainAstakineVibrio alginolyticusWhite spot syndrome virusHemocytesImmunization
原始语种摘要: Abstract(#br)Astakine is a crucial factor in the proliferation and differentiation of hematopoietic stem cells and is directly involved in hematopoiesis in crustaceans. To assess the role of Astakine in the innate immune system of Scylla paramamosain , the immune responses in healthy and Astakine-inhibited S. paramamosain were investigated in the present study. The RNA transcripts of Astakine were widely distributed in all examined tissues, with significantly higher levels of expression in hemocytes of both healthy and challenged S. paramamosain with Vibrio alginolyticus and WSSV. When Astakine was knocked down by RNA interference technology, immune-related genes, including Janus kinase , prophenoloxidase , hemocyanin , β-actin , myosin II essential light chain-like protein , signal...
全文获取路径: Elsevier  (合作)
影响因子:2.964 (2012)

  • virus 病毒
  • white 白色
  • against 反对
  • infection 感染
  • syndrome 症候群