Treatment response and prognosis of POEMS syndrome coexisting with Castleman disease
诗证并存Castleman病的治疗反应及预后
作者: Tomoki SuichiSonoko MisawaYukari SekiguchiKazumoto ShibuyaAtsuko TsuneyamaYo-ichi SuzukiKeigo NakamuraHiroki KanoSatoshi Kuwabara
作者单位: 1Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
刊名: Journal of the Neurological Sciences, 2020, Vol.413
来源数据库: Elsevier Journal
DOI: 10.1016/j.jns.2020.116771
关键词: POEMS syndromeCastleman diseasePrognosis
英文摘要: Abstract(#br)POEMS (polyneuropathy, organomegaly, endocrinopathy monoclonal gammopathy, and skin changes) syndrome is occasionally associated with Castleman disease (CD) and their prognosis is considered as poorer than that in POEMS alone patients. To elucidate recent prognosis of POEMS syndrome coexisting with CD, we reviewed clinical data of 102 patients with POEMS syndrome treated at our institution between 2000 and 2018 and compared clinical characteristics, response to treatment, and prognosis between POEMS patients with biopsy-proven CD (POEMS-CD) and those without it. Fourteen POEMS-CD patients and 56 POEMS alone patients were identified, and the remaining 32 patients with unbiopsied lymphadenopathy were excluded. POEMS-CD patients significantly showed earlier onset and less severe...
全文获取路径: Elsevier  (合作)
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影响因子:2.243 (2012)

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关键词翻译
关键词翻译
  • prognosis 预报
  • syndrome 症候群
  • coexisting 同时存在
  • disease 
  • response 响应