Association of glucose homeostasis and metabolic syndrome with knee cartilage defects and cartilage volume in young adults
作者: Tao MengBenny AntonyAlison VennBrooklyn FraserFlavia CicuttiniLyn MarchMarita CrossTerence DwyerGraeme JonesLaura L. LaslettChanghai Ding
作者单位: 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
2Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
3Institute of Bone and Joint Research, University of Sydney, Sydney, Australia
4The George Institute for Global Health, University of Oxford, Oxford, United Kingdom
5Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China
刊名: Seminars in Arthritis and Rheumatism, 2020, Vol.50 (2), pp.192-197
来源数据库: Elsevier Journal
DOI: 10.1016/j.semarthrit.2019.10.001
关键词: Glucose homeostasisMetabolic syndromeKnee cartilageYoung adults
原始语种摘要: Abstract(#br)Objective(#br)To describe the associations of glucose homeostasis and metabolic syndrome (MetS) measures with knee cartilage defects and cartilage volume in young adults.(#br)Methods(#br)Fasting blood biochemistry, waist circumference and blood pressure measures were collected 4–5 years prior to knee magnetic resonance imaging (MRI) scans. Blood measures included levels of glucose, insulin, triglyceride and high-density lipoprotein cholesterol (HDL-C). Homeostatic model assessment 2-insulin resistance (HOMA2-IR), HOMA2-beta cell function (HOMA2-β), HOMA2-insulin sensitivity (HOMA-S) and MetS were calculated or defined. Knee cartilage defects and cartilage volume were measured from MRI scans. Data were analysed using log binomial or linear regressions.(#br)Results(#br)Among...
全文获取路径: Elsevier  (合作)
影响因子:3.806 (2012)

  • homeostasis 体内平衡
  • glucose 葡萄糖
  • cartilage 软骨
  • insulin 胰岛素
  • tibiofemoral 胫腿节的
  • metabolic 新陈代谢的
  • fasting 禁食
  • hyperglycaemia 高8糖
  • circumference 圆周
  • waist 紧身胸衣