The influence of adrenergic blockade in rats with apical periodontitis under chronic stress conditions
作者: Rayana Duarte KhouryRenata Falchete do PradoFelipe de Souza MatosBruna Ribas de MeirelesFlávia Goulart da Rosa CardosoLuciane Dias de OliveiraCláudio Antonio Talge CarvalhoMarcia Carneiro Valera
作者单位: 1Department of Restorative Dentistry, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, SP, Brazil
刊名: Archives of Oral Biology, 2020, Vol.110
来源数据库: Elsevier Journal
DOI: 10.1016/j.archoralbio.2019.104590
关键词: Chronic stressApical periodontitisAdrenergic blockersPropranololPhentolamine
原始语种摘要: Abstract(#br)Objective(#br)To investigate the influence of chronic stress and adrenergic blockade in a rat model of apical periodontitis.(#br)Methods(#br)Thirty-two Wistar rats were submitted to an animal model of periapical lesion and randomly divided into 4 groups (n = 8): no stress (NS); stress + saline solution (SS); stress + β-adrenergic blocker (Sβ); stress + α-adrenergic blocker (Sα). The SS, Sβ and Sα groups were submitted to an animal model of chronic stress for 28 days and received daily injections of saline solution, propranolol (β adrenergic blocker) and phentolamine (α adrenergic blocker), respectively. After 28 days the animals were euthanized and the following analyses were carried out: a) serum corticosterone levels through Radioimmunoassay; b) measurement of serum levels...
全文获取路径: Elsevier  (合作)
影响因子:1.549 (2012)

  • 普萘洛尔 过熔
  • periodontitis 牙周炎
  • adrenergic 肾上腺素性的
  • stress 应力
  • blockade 封闭
  • injections 用政府支出来刺激需求增长
  • superfusion 过熔
  • propranolol 过熔
  • chronic 延续很长的
  • blocker 间苗器
  • apical 顶端的