Awake Sedation With Propofol Attenuates Intraoperative Stress of Carotid Endarterectomy in Regional Anesthesia
作者: Péter SzabóMátyás MayerZoltán Horváth-SzalaiKrisztina TóthSándor MártonGábor MenyheiLászló SínayTihamér Molnár
作者单位: 1Department of Anesthesiology and Intensive Care, Medical School, University of Pécs, Pécs, Hungary
2Department of Forensic Medicine, Medical School, University of Pécs, Pécs, Hungary
3Depatment of Laboratory Medicine, Medical School, University of Pécs, Pécs, Hungary
4Department of Vascular Surgery, Medical School, University of Pécs, Pécs, Hungary
刊名: Annals of Vascular Surgery, 2020, Vol.63 , pp.311-318
来源数据库: Elsevier Journal
DOI: 10.1016/j.avsg.2019.06.047
英文摘要: Background(#br)Carotid endarterectomy in regional anesthesia is often associated with increased perioperative stress. We assumed that carotid endarterectomy performed under awake sedation with propofol is more beneficial to prevent such stress than alprazolam premedication only.(#br)Methods(#br)A total of 47 consecutive patients with significant carotid artery stenosis were enrolled into this investigation and followed up for 5 years to explore vascular complications. All operations were performed under regional anesthesia. As premedication, all patients took 0.5 mg of alprazolam 30 minutes before the procedure. After randomization, 22 patients had awake sedation with target controlled propofol infusion, and the other 25 had only premedication. Cortisol plasma levels were serially...
全文获取路径: Elsevier  (合作)
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影响因子:0.985 (2012)

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