Kinetic analysis of human metallothionein and CdTe quantum dot complexes using fluorescence and voltammetry techniques
作者: Ewelina GuszpitLudmila KrejčováSoňa KřížkováMarta KepinskaLukáš RichteraPavel KopelVojtěch AdamHalina Milnerowicz
作者单位: 1Department of Biomedical and Environmental Analysis, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland
2Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemendelska 1/1665, 613-00 Brno, Czech Republic
3Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612-00 Brno, Czech Republic
刊名: Colloids and Surfaces B: Biointerfaces, 2017, Vol.160 , pp.381-389
来源数据库: Elsevier Journal
DOI: 10.1016/j.colsurfb.2017.09.033
关键词: Quantum dotsMetallothioneinBioconjugationBiomarkersElectrochemistryDifferential pulse voltammetry
原始语种摘要: Abstract(#br)Thanks to quantum dots’ (QDs) properties, they can be used as selective and sensitive biomarkers in molecular imaging. In a previous paper, we confirmed the possibility of interaction between mercaptosuccinic acid-capped cadmium telluride QDs (MSA-CdTe) and human metallothionein (MT). The aim of this study was to expand on our previous research with an evaluation of the stability of the formed complexes between human MT and four CdTe compounds of the following sizes: 3.4nm (blue QDs), 3.8nm (green QDs), 4.5nm (yellow QDs), and 5.2nm (red QDs). Complexes were evaluated over time using fluorescence intensity and differential pulse voltammetry. Differences between the voltammograms obtained for standard...
全文获取路径: Elsevier  (合作)
影响因子:3.554 (2012)

  • complexes 联合企业
  • fluorescence 荧光
  • voltammetry 伏安测量法
  • observed 观察到的
  • human 人的
  • conjugation 共轭
  • confirmed 已确认的
  • whereas 鉴于
  • intensity 强度
  • interaction 相互酌