Correlation between estrogen plasma level and miRNAs in muscle of Piedmontese cattle
作者: E. MartignaniS. MirettiL. VincentiM. Baratta
作者单位: 1Department of Veterinary Science, University of Torino, Largo Braccini 2, 10095 Grugliasco, TO, Italy
刊名: Domestic Animal Endocrinology, 2019, Vol.67 , pp.37-41
来源数据库: Elsevier Journal
DOI: 10.1016/j.domaniend.2018.12.005
关键词: 17β-estradiolCattleMicroRNASkeletal muscle
英文摘要: Abstract(#br)A loss-of-function mutation of the myostatin gene has a very high prevalence in the Piedmontese cattle breed. The effect of such mutation is a double-muscle phenotype because of hypertrophy. However, differences in muscle mass development can still be detected in individuals of this breed. Such differences must be generated by other factors controlling skeletal muscle development. MicroRNAs are short noncoding RNA molecules that modulate gene expression at a post-transcriptional level. MicroRNAs have been demonstrated to be involved in skeletal muscle development, and some of them are controlled by steroid hormone signaling. Data on estrogen signaling are lacking, whereas more studies have been carried out on the effect of androgens. We aimed at identifying putative estrogen...
全文获取路径: Elsevier  (合作)
影响因子:2.377 (2012)

  • estrogen 雌激素
  • muscle 肌肉
  • plasma 深绿玉髓
  • cattle 
  • level 水准
  • between 在中间