|作者：||Anna Torres, Estel Gelabert, Alba Roca, Purificación Navarro, Anna Plaza, Susana Subirà, Rocío Martin-Santos, Carlos Ascaso, Lluïsa Garcia-Esteve|
1Unitat de Salut Mental Perinatal CLINIC-BCN, Hospital Clínic. Barcelona, Spain
2Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Barcelona, Spain
3Department of Psychiatry and Clinical Psychology, Universitat de Barcelona. Barcelona, Spain.
4Department of Clinical and Health Psychology. Universitat Autònoma de Barcelona. Bellaterra, Spain
5Servei de Psicologia, Regidoria de Polítiques de Gènere Ajuntament de Terrassa. Terrassa, Spain.
6Unitat de Crisi i Prevenció del Suicidi, CPB-Dreta Eixample. Barcelona, Spain
7Department of Psychiatry and Clinical Psychology, Hospital Clinic, Barcelona, Spain
8Department of Medicine, Universitat de Barcelona. Barcelona, Spain
9Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), Spain.
10Biostatistics Unit, Public Health Department, Universitat de Barcelona. Barcelona, Spain
|刊名：||Journal of Affective Disorders, 2018|
|关键词：||Postpartum depression; Course; Risk factors; Longitudinal study;|
|原始语种摘要：||Abstract(#br)Background(#br)Survival methodology has not already been used in studies about postpartum depression (PPD) course. The aims of the present study were to estimate the duration of a Major Postpartum Depressive Episode (MPDE) during 2 years, as well as to explore factors associated with the course.(#br)Method(#br)This was a prospective, naturalistic, longitudinal study with a cohort of 165 women with a MPDE (DSM-IV criteria). Potential predictors of prognosis were recorded at baseline. Follow-up was conducted using the Longitudinal Interval Follow-up Evaluation (LIFE).(#br)Results(#br)Of the total sample, 110 (66.7%) completed the 2 years follow-up. The mean time to full remission was 49.4 weeks (95%CI: 44.0 - 59.8). The probability of recovering was 30.2% (95% CI: 22.1%-37.4%)... at 6 months of follow-up, 66.3% (95% CI: 57.4% - 73.4%) at 12 months of follow-up, and 90.3% (95% CI: 79.8% - 95.4%) at 24 months of follow-up. Mothers with financial difficulties, onset of depressive episode previous to birth, and those with prior treated depressive episodes took longer in achieving full remission.(#br)Limitations(#br)Results are only generalizable to mothers with PPD treated in a psychiatric outpatient setting. Psychopharmacological treatment was uncontrolled and personality was not assessed.(#br)Conclusions(#br)Our findings suggest that PPD could become a chronic disorder, particularly in mothers with an onset of the episode previous to birth, with a history of depression or with financial problems. Knowledge of these factors may help to improve the guidelines of depression management and treatment during the perinatal period.|