Incorporating N-acetylcysteine and tricalcium phosphate into epoxy resin-based sealer improved its biocompatibility and adhesiveness to radicular dentine
作者: Carlos Henrique Ribeiro CamargoLaís Carolina Landim GomesMonique Costa Moreira FrançaTatiane Sampaio BittencourtMarcia Carneiro ValeraSamira Esteves Afonso CamargoMarco Cicero Bottino
作者单位: 1Department of Restorative Dental Sciences, University of Florida, College of Dentistry, Gainesville, FL, USA
2Department of Restorative Dentistry, Sao Paulo State University, School of Dentistry, Sao Jose dos Campos, SP, Brazil
3Department of Cariology, Restorative Sciences & Endodontics, University of Michigan, School of Dentistry, Ann Arbor, MI, USA
刊名: Dental Materials, 2019, Vol.35 (12), pp.1750-1756
来源数据库: Elsevier Journal
DOI: 10.1016/
关键词: Radicular dentineAdhesionBiocompatibilityEndodonticsN -AcetylcysteineTricalcium phosphateRetro-Filling material
原始语种摘要: Abstract(#br)Objective(#br)This in vitro study was designed to evaluate the biocompatibility, adhesiveness, and antimicrobial activity of epoxy resin-based sealer associated with N-Acetylcysteine (NAC) or beta-tricalcium phosphate nanoparticles (β-TCP) as an experimental retro-filling material.(#br)Methods(#br)Cytotoxicity was assessed using 2,3-Bis-(Methoxy-4-Nitro-5-Sulphophenyl)-2H-Tetrazolium-5-Carboxanilide (XTT) and Sulforhodamine B (SRB) assays after exposing human periodontal ligament fibroblasts to extracts of the materials for 1, 3, or 7 days. For the adhesive resistance test, root canals (48 single-root teeth) were instrumented with Reciproc #40 files (VDW GmbH, Germany) and obturated. After 7 days, the apices were sectioned and a retrograde cavity prepared and filled with the...
全文获取路径: Elsevier  (合作)
影响因子:3.773 (2012)

  • sealer 密封器
  • phosphate 磷酸盐
  • dentine 牙质
  • tricalcium 三钙
  • radicular 胚根的
  • endodontic 牙髓学的
  • acetylcysteine 乙酰半胱胺酸
  • antimicrobial 杀菌剂
  • resin 
  • epoxy 环氧尸