Modelling nasal high flow therapy effects on upper airway resistance and resistive work of breathing
作者: Cletus F. AdamsPatrick H. GeogheganCallum J. SpenceMark C. Jermy
作者单位: 1Department of Mechanical Engineering, University of Canterbury, Christchurch 8041, New Zealand
2Fisher and Paykel Healthcare Limited, 15 Maurice Paykel Place, Auckland 2013, New Zealand
3School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, England, United Kingdom
刊名: Respiratory Physiology & Neurobiology, 2018, Vol.254 , pp.23-29
来源数据库: Elsevier Journal
DOI: 10.1016/j.resp.2018.03.014
关键词: Nasal high flow therapyWork of breathingZero pressure inspiratory flow
原始语种摘要: Abstract(#br)Aim(#br)The goal of this paper is to quantify upper airway resistance with and without nasal high flow (NHF) therapy. For adults, NHF therapy feeds 30–60 L/min of warm humidified air into the nose through short cannulas which do not seal the nostril. NHF therapy has been reported to increase airway pressure, increase tidal volume ( V t ) and decrease respiratory rate (RR), but it is unclear how these findings affect the work done to overcome airway resistance to air flow during expiration. Also, there is little information on how the choice of nasal cannula size may affect work of breathing. In this paper, estimates of airway resistance without and with different NHF flow (applied via different cannula sizes) were made. The breathing efforts required to overcome airway...
全文获取路径: Elsevier  (合作)
影响因子:2.051 (2012)

  • airway 航路
  • breathing 通风
  • inspiratory 吸气的
  • expiratory 吐气的
  • resistance 抵抗
  • required 必需
  • overcome 克服
  • upper 上面的
  • cannula 套管
  • nasal 鼻的