Harmonization of neuroimaging biomarkers for neurodegenerative diseases: A survey in the imaging community of perceived barriers and suggested actions
作者: Jorge JovicichFrederik BarkhofClaudio BabiloniKarl HerholzChristoph MulertBart N.M. van BerckelGiovanni B. Frisoni
作者单位: 1Center for Mind/Brain Sciences, University of Trento, Trento, Italy
2Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
3Insititutes of Neurology and Healthcare Engineering, University College London, London, United Kingdom
4Department of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Rome, Italy
5Department of Neuroscience, IRCCS-Hospital San Raffaele Pisana of Rome and Cassino, Rome and Cassino, Italy
6Division of Neuroscience & Experimental Psychology, University of Manchester, Manchester, United Kingdom
7Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
8Department of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
9Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Fatebenefratelli, Brescia, Italy
10Memory Clinic and LANVIE Laboratory of Neuroimaging of Ag
刊名: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019, Vol.11 , pp.69-73
来源数据库: Elsevier Journal
DOI: 10.1016/j.dadm.2018.11.005
关键词: SurveyNeurodegenerationBiomarkerMulticentricMultisiteNeuroimagingHarmonizationMagnetic resonance imagingMRIPositron emission tomographyPETPhoton emission computed tomographySPECTElectroencephalographyEEG
英文摘要: Abstract(#br)Introduction(#br)Molecular, functional, and structural neuroimaging biomarkers are largely used to study neurodegenerative diseases, but their benefits to patients/science might be greatly enhanced by improving standardization and cross-validation. In this EU Joint Programme-Neurodegenerative Diseases Research–funded project, we surveyed the neuroimaging community to assess perceived barriers in multicentric neuroimaging harmonization and actions to overcome them.(#br)Methods(#br)An anonymous survey addressed researchers, clinicians, pharma industry, and professional associations, inquiring about both general and modality-specific harmonization barriers.(#br)Results(#br)Survey participants (459) represented an international (37 countries) multidisciplinary community. We...
全文获取路径: Elsevier  (合作)

  • barriers 势垒
  • community 群落
  • actions 对策
  • suggested 建议
  • survey