Biofilm mechanics: Implications in infection and survival
作者: Erin S. GloagStefania FabbriDaniel J. WozniakPaul Stoodley
作者单位: 1Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA
2Perfectus Biomed, SciTech Daresbury, Cheshire, WA4 4AB, UK
3Department of Microbiology, The Ohio State University, Columbus, OH, 43210, USA
4Department of Orthopedics, The Ohio State University, Columbus, OH, 43210, USA
5National Biofilm Innovation Centre (NBIC) and National Centre for Advanced Tribology at Southampton (nCATS), University of Southampton, Southampton, SO17 1BJ, UK
刊名: Biofilm, 2020, Vol.2
来源数据库: Elsevier Journal
DOI: 10.1016/j.bioflm.2019.100017
关键词: BiofilmMechanicsViscoelasticityBiophysicsExtracellular matrixExtracellular polymeric substanceTolerancePersistence
英文摘要: Abstract(#br)It has long been recognized that biofilms are viscoelastic materials, however the importance of this attribute to the survival and persistence of these microbial communities is yet to be fully realized. Here we review work, which focuses on understanding biofilm mechanics and put this knowledge in the context of biofilm survival, particularly for biofilm-associated infections. We note that biofilm viscoelasticity may be an evolved property of these communities, and that the production of multiple extracellular polymeric slime components may be a way to ensure the development of biofilms with complex viscoelastic properties. We discuss viscoelasticity facilitating biofilm survival in the context of promoting the formation of larger and stronger biofilms when exposed to shear...
全文获取路径: Elsevier  (合作)

  • survival 生存
  • infection 感染
  • mechanics 力学