Organogel composed of poloxamer 188 and passion fruit oil: Sol-gel transition, rheology, and mechanical properties
作者: Lizziane Maria Belloto de FranciscoHélen Cássia RossetoLucas de Alcântara Sica de ToledoRafaela Said dos SantosSabrina Barbosa de Souza FerreiraMarcos Luciano Bruschi
作者单位: 1Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringa, 87020-900 Maringa, Parana, Brazil
刊名: Journal of Molecular Liquids, 2019, Vol.289
来源数据库: Elsevier Journal
DOI: 10.1016/j.molliq.2019.111170
关键词: OrganogelPoloxamer 188Passion fruit oilSol-gel transitionRheologyTexture profile analysis
原始语种摘要: Abstract(#br)The present work at hands deals with physicochemical properties of an organogel composed of non-ionic triblock copolymer poloxamer 188 and passion fruit oil. To provide the characterization it was investigated the rheological (continuous shear and oscillatory) properties, sol-gel transition temperature, mechanical properties (hardness, compressibility, adhesiveness, cohesiveness and elasticity) and softness index. Moreover, we investigated the possible correlation between the rheological and mechanical characteristics to study the structuring of formulations and to select the best organogel for pharmaceutical applications. Mechanical and rheological characteristics showed to be temperature, polymer and oil concentration dependent. The increase of poloxamer 188 and passion...
全文获取路径: Elsevier  (合作)
影响因子:1.684 (2012)

  • transition 转移
  • rheology 龄学
  • poloxamer 泊洛沙姆
  • composed 沉着的
  • mechanical 机械的
  • properties 道具
  • passion 热情
  • profile 纵断图
  • fruit 水果
  • analysis 分析