Safety of Peripheral Line Administration of 3% Hypertonic Saline and Mannitol in the Emergency Department
作者: Elhaam MesghaliScott FitterKhaled BahjriKayvan Moussavi
作者单位: 1Loma Linda University School of Pharmacy, Loma Linda, California
2Loma Linda University Medical Center, Loma Linda, California
3Department of Pharmaceutical and Administrative Sciences, Loma Linda University School of Pharmacy, Loma Linda, California
4Department of Pharmacy Practice, Marshall B. Ketchum University College of Pharmacy, Fullerton, California
刊名: Journal of Emergency Medicine, 2019, Vol.56 (4), pp.431-436
来源数据库: Elsevier Journal
DOI: 10.1016/j.jemermed.2018.12.046
关键词: Hypertonic salineMannitolIntravenousEmergency departmentMedication safetyExtravasation
英文摘要: Abstract(#br)Background(#br)Hypertonic saline (HTS) and mannitol are frequently utilized in the emergency department (ED) to manage elevations in intracranial pressure (ICP).(#br)Objective(#br)The objective of this study was to compare the incidence of extravasation injury when HTS or mannitol was administered via peripheral i.v. line (PIV).(#br)Methods(#br)This retrospective cohort study evaluated adult and pediatric patients given either 3% HTS or mannitol via PIV while in the ED. The primary outcome was extravasation incidence.(#br)Results(#br)One hundred and ninety-two patients were included, of which 85 (44%) received HTS and 107 (56%) received mannitol. Patients who received HTS were younger (27.5 ± 24.3 years vs. 53.9 ± 22.3 years; p < 0.001); 55.3% of patients given HTS received...
全文获取路径: Elsevier  (合作)
影响因子:1.331 (2012)