Ultrasound sonication prior to electrospinning tailors silk fibroin/PEO membranes for periodontal regeneration
作者: Ricardo SerôdioSónia L. SchickertAna R. Costa-PintoJuliana R. DiasPedro L. GranjaFang YangAna L. Oliveira
作者单位: 1CBQF - Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Porto, Portugal
2Department of Regenerative Biomaterials, Radboud University Medical Center, Nijmegen, the Netherlands
3i3s – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal
4CDRsp – Centro para o Desenvolvimento Rápido e Sustentado do Produto, Instituto Politécnico de Leiria, Portugal
刊名: Materials Science & Engineering C, 2019, Vol.98 , pp.969-981
来源数据库: Elsevier Journal
DOI: 10.1016/j.msec.2019.01.055
关键词: Silk fibroinPoly(ethylene oxide) membranePeriodontal regenerationElectrospinningUltrasound sonication
英文摘要: Abstract(#br)In this study, silk fibroin (SF)/poly(ethylene oxide) (PEO) membranes were designed and fabricated by combining ultrasound sonication prior to electrospinning (0 to 20 min) as a strategy to physically control the rheological properties of solutions (10 to 30% w/v PEO) and to improve the spinnability of the system. PEO has proved to be essential as a co-spinning agent to assure good membrane reproducibility and enough flexibility for clinical manipulation.(#br)The rheological tests indicated that sonication greatly increased the viscosity of SF/PEO solutions and further enhanced the quality of the produced electrospun fibers with consequent improved mechanical properties in dry and wet conditions. By tuning the viscosity of the solutions using a simple sonication step prior to...
全文获取路径: Elsevier  (合作)
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影响因子:2.404 (2012)

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关键词翻译
关键词翻译
  • fibroin 丝蛋白
  • regeneration 再生
  • sonication 声裂法
  • periodontal 牙周病学
  • ethylene 乙烯
  • membrane 
  • prior 预[优]先
  • oxide 氧化物