White matter and its relationship with cognition in subjective cognitive decline
作者: Lisa OhlhauserAshleigh F. ParkerColette M. SmartJodie R. Gawryluk
作者单位: 1Department of Psychology, University of Victoria, Victoria, British Columbia, Canada
刊名: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019, Vol.11 , pp.28-35
来源数据库: Elsevier Journal
DOI: 10.1016/j.dadm.2018.10.008
关键词: Subjective cognitive declineDiffusion tensor imagingExecutive functionMemoryAlzheimer's disease
英文摘要: Abstract(#br)Introduction(#br)Subjective cognitive decline (SCD) is the earliest stage on the continuum toward Alzheimer's disease. This study examined (1) differences in white matter integrity between individuals with SCD and healthy control subjects and (2) how white matter integrity related to memory and executive function.(#br)Methods(#br)Diffusion tensor imaging and neuropsychological assessment data were retrieved from the Alzheimer's Disease Neuroimaging Initiative database for 30 individuals with SCD and 44 control subjects.(#br)Results(#br)Results revealed significantly lower white matter integrity in individuals with SCD relative to control subjects in widespread regions, including the bilateral corticospinal tracts, superior and inferior longitudinal fasciculi, fronto-occipital...
全文获取路径: Elsevier  (合作)

  • cognition 认识
  • White 怀特牌汽车
  • relationship 关系
  • matter 物质
  • subjective 舟的
  • decline 推辞
  • cognitive 修]认知[识