The association of preoperative thyroid-stimulating hormone level and the risk of differentiated thyroid cancer in patients with thyroid nodules: A systematic review and meta-analysis
作者: Anping SuWanjun ZhaoWenshuang WuTao WeiMeifang RuanZhihui LiJingqiang Zhu
作者单位: 1Department of Thyroid and Parathyroid Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
2Department of Medical Affairs, Merck Serono Co., Ltd, Beijing, China
刊名: The American Journal of Surgery, 2020
来源数据库: Elsevier Journal
DOI: 10.1016/j.amjsurg.2020.01.009
关键词: Differentiated thyroid cancerPreoperativeThyroid carcinomaThyroid nodulesThyroid-stimulating hormone
原始语种摘要: Abstract(#br)Background(#br)This systematic review and meta-analysis was conducted to determine the value of preoperative thyroid-stimulating hormone (TSH) levels in assessing the risk of differentiated thyroid cancer (DTC) in patients with thyroid nodules.(#br)Methods(#br)This meta-analysis included 23,799 subjects (15,406 non-Chinese and 8393 Chinese) with thyroid nodules. Multivariate and individual adjusted odds ratios (OR) were calculated for a 1 mU/L increase in preoperative TSH levels to determine the risk of malignant DTC.(#br)Results(#br)The OR for DTC in relation to preoperative TSH levels was significant in Chinese (1.25 [1.11, 1.40], Z = 3.67, p = 0.0002) and non-Chinese subjects (1.12 [1.03, 1.22], Z = 2.72, p = 0.006). The overall random-effects model indicated that there...
全文获取路径: Elsevier  (合作)
影响因子:2.516 (2012)

  • preoperative 操作前的
  • stimulating 促进
  • thyroid 甲状腺
  • nodules 瘤状体
  • hormone 激素
  • differentiated 区别
  • cancer 癌症
  • systematic 有系统的
  • association 联合
  • review 复审