Host-defense and trefoil factor family peptides in skin secretions of the Mawa clawed frog Xenopus boumbaensis (Pipidae)
作者: J. Michael ConlonMilena MechkarskaJolanta KolodziejekJérôme LeprinceLaurent CoquetThierry JouenneHubert VaudryNorbert NowotnyJay D. King
作者单位: 1SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
2Department of Biochemistry, College of Medicine and Health Sciences, United Arab Emirates University, 17666 Al Ain, United Arab Emirates
3Viral Zoonoses, Emerging and Vector-Borne Infections Group, Institute of Virology, University of Veterinary Medicine, Veterinärplatz 1, A-1210 Vienna, Austria
4INSERM U-982, PRIMACEN, CNRS, IRIB, University of Rouen, 76821 Mont-Saint-Aignan, France
5PISSARO, Institute for Research and Innovation in Biomedicine (IRIB) CNRS UMR 6270, University of Rouen, 76821 Mont-Saint-Aignan, France
6Department of Microbiology and Immunology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman
7Rare Species Conservatory Foundation, St. Louis, MO 63110, USA
刊名: Peptides, 2015, Vol.72 , pp.44-49
来源数据库: Elsevier Journal
DOI: 10.1016/j.peptides.2015.03.025
关键词: Host-defenseFrog skinPipidaePolyploidyXenopusTrefoil factor family
原始语种摘要: Abstract(#br)Peptidomic analysis of norepinephrine-stimulated skin secretions from the octoploid Mawa clawed frog Xenopus boumbaensis Loumont, 1983 led to the identification and characterization of 15 host-defense peptides belonging to the magainin (two peptides), peptide glycine-leucine-amide (PGLa; three peptides), xenopsin precursor fragment (XPF; three peptides), caerulein precursor fragment (CPF; two peptides), and caerulein precursor fragment-related peptide (CPF-RP; five peptides) families. In addition, caerulein and three peptides with structural similarity to the trefoil factor family (TFF) peptides, xP2 and xP4 from Xenopus laevis were also present in the secretions. Consistent with data from comparisons of the nucleotides sequence of mitochondrial and nuclear genes, the primary...
全文获取路径: Elsevier  (合作)
影响因子:2.522 (2012)

  • clawed 有爪的
  • family 
  • factor 因素
  • xenopsin 爪蟾降压肽
  • trefoil 车轴草
  • caerulein 蛙皮素
  • defense 防备
  • fragment 碎屑
  • allopatric 在给发生的
  • precursor 前驱物质