Malignant peripheral nerve sheath tumor arising in schwannomatosis with multiple lung metastases
作者: Yuhui Ding
作者单位: 1Department of Neurosurgery Tianjin Medical University General Hospital, , 300052, No.154 Anshan Road, Heping District, Tianjin, China
刊名: World Neurosurgery, 2018
来源数据库: Elsevier Journal
DOI: 10.1016/j.wneu.2018.08.087
关键词: SMARCB1Malignant peripheral nerve sheath tumorMPNSTSchwannomatosisIntraspinalLung metastasis
英文摘要: Abstract(#br)Background(#br)Malignant peripheral nerve sheath tumor(MPNST) is a kind of rare neurogenic malignancy which usually arises from nerve fibers in any tissue and organ that have nerve fiber distributions especially trunk and extremities but extremely rare in spinal canal.(#br)Case Description(#br)We report a 30-year-old woman, had a history of excision of intraspinal occupying lesions 5 times and the pathological diagnosis based on histomorphologic and immunohistochemistry was schwannomatosis which existed in her family history. Unfortunately, she died because her condition deteriorated rapidly and appeared multiple lung metastases. MPNST was confirmed by needle biopsy of lung lesions.(#br)Conclusions(#br)Many cases of MPNST usually developed from neurofibromatosis type 1(NF1)....
全文获取路径: Elsevier  (合作)
影响因子:1.765 (2012)

  • peripheral 周边的
  • nerve 叶脉
  • metastases 移位变化
  • sheath 
  • tumor 肿胀
  • multiple 多次的