Heteroannulation through combined palladium catalysed and Friedel-Crafts reactions strategy: Synthesis of 3-alkylidene isoindolin-1-ones
作者: Nitya G. KunduM.Wahab KhanRupa Mukhopadhyay
作者单位: 1Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Calcutta - 700 032, India.
刊名: Tetrahedron, 1999, Vol.55 (42), pp.12361-12376
来源数据库: Elsevier Journal
DOI: 10.1016/S0040-4020(99)00719-X
原始语种摘要: Abstract(#br)The palladium-catalysed reactions of 2-iodobenzamides 1–5 with trimethylsilyl acetylene 6 led to 2-(2-trimethylsilyl)ethynyl benzamides 7–11 in excellent yields. The 2-(2-trimethylsilyl)ethynyl benzamides 7–11 underwent Friedel-Crafts reactions with acid chlorides 12–17 or anhydride 18 smoothly under mild conditions yielding the 3-alkylidene isoindolin-1-ones 19–38 .
全文获取路径: Elsevier  (合作)
影响因子:2.803 (2012)

  • 优秀的 顺利地
  • alkylidene 次烷基
  • palladium 
  • ethynyl 乙炔基
  • acetylene 乙炔
  • yielding 收获量
  • anhydride 无水物
  • smoothly 顺利地
  • excellent 顺利地
  • combined 组合
  • strategy 战略