Androgen deprivation therapy in men with node-positive prostate cancer treated with postoperative radiotherapy
雄激素剥夺疗法对结节性前列腺癌术后放疗的男性
作者: Carlo Andrea BraviAmy TinEmily VertosickElio MazzoneMarco BandiniPaolo Dell'OglioArmando StabileGiorgio GandagliaNicola FossatiDaniel SjobergKarim TouijerCesare CozzariniAlberto BrigantiFrancesco MontorsiJames EasthamAndrew Vickers
作者单位: 1Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy
2Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
3Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY
4Department of Radiotherapy, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy
刊名: Urologic Oncology: Seminars and Original Investigations, 2020, Vol.38 (4), pp.204-209
来源数据库: Elsevier Journal
DOI: 10.1016/j.urolonc.2019.09.018
关键词: Node-positive prostate cancerRadical prostatectomyAndrogen deprivation therapyPostoperative radiotherapy
原始语种摘要: Abstract(#br)Background(#br)In men with node-positive prostate cancer after radical prostatectomy there are limited data on the value of adding androgen deprivation therapy (ADT) to postoperative radiotherapy.(#br)Objective(#br)To determine whether there is a clear oncologic benefit to ADT in the setting of node-positive prostate cancer treated with postoperative radiotherapy.(#br)Methods(#br)We analyzed data for 372 prostate cancer patients treated at San Raffaele Hospital with postoperative radiotherapy for node-positive disease after radical prostatectomy, 272 received both ADT and radiotherapy. Eighty-six men were followed without an event for more than 10 years.(#br)Results(#br)Patients who received postoperative radiotherapy + ADT had more aggressive disease, with higher...
全文获取路径: Elsevier  (合作)
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关键词翻译
关键词翻译
  • radiotherapy 放射线疗法
  • prostate 前列腺
  • postoperative 手术后的
  • deprivation 丧失
  • treated 加工的
  • cancer 癌症
  • positive 阳片
  • androgen 雄激素
  • survival 生存
  • clinically 临床上