Drying of a single droplet of dextrin: Drying kinetics modeling and particle formation
作者: Belal Al ZaitoneAbdulrahim Al-ZahraniSaad Al-ShahraniAlf Lamprecht
作者单位: 1Department of Chemical and Materials Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia
2Department of Pharmaceutics, Institute of Pharmacy, University of Bonn, Germany
刊名: International Journal of Pharmaceutics, 2020, Vol.574
来源数据库: Elsevier Journal
DOI: 10.1016/j.ijpharm.2019.118888
关键词: Single droplet dryingAcoustic levitationParticle formationDrying kinetics modelling
原始语种摘要: Abstract(#br)Powder production by spray drying is achieved through the dehydration of droplets. The physical properties of the dried powder often influence its application. The drying kinetics of a single droplet of dextrin solution into the solid phase were monitored during the drying process. An acoustic levitator was used to suspend the droplet in the acoustic field. Such experiments are essential for achieving a fundamental understanding of the drying process. Droplets with different initial solid content (dextrin aqueous solution of 10% and 30%) were investigated at different gas drying temperatures. The drying curves were compared to the Reaction Engineering Approach (REA) model. A good agreement between the model prediction and the experimental results was demonstrated, with an...
全文获取路径: Elsevier  (合作)
影响因子:3.458 (2012)