The kisspeptin system in domestic animals: what we know and what we still need to understand of its role in reproduction
作者: M. BeltramoV. RobertC. Decourt
作者单位: 1INRAE (CNRS, UMR7247, Université de Tours, IFCE), UMR85 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France
刊名: Domestic Animal Endocrinology, 2020
来源数据库: Elsevier Journal
DOI: 10.1016/j.domaniend.2020.106466
关键词: KisspeptinReproductionOvulationGnRHLHAgonist
英文摘要: Abstract(#br)The discovery of the kisspeptin (Kp) system stirred a burst of research in the field of reproductive neuroendocrinology. In the last 15 yr, the organization and activity of the system, including its neuroanatomical structure, its major physiological functions, and its main pharmacological properties, were outlined. To this endeavor, the use of genetic tools to delete and to restore Kp system functionality in a specific tissue was essential. At present, there is no question as to the key role of the Kp system in mammalian reproduction. However, easily applicable genetic manipulations are unavailable for domestic animals. Hence, many essential details on the physiological mechanisms underlying its action on domestic animals require further investigation. The potentially...
全文获取路径: Elsevier  (合作)
影响因子:2.377 (2012)

  • understand 理解
  • domestic 国产的
  • reproduction 复制
  • still 
  • system