Anti-inflammatory Effects of Saxifrage Cream in Hapten-induced Chronic Dermatitis-eczema in Mice
作者: Jun YangYong-Ai XiongShi-Ji XiaoYing-Shu Xu
作者单位: 1School of Pharmacy, Zunyi Medical University, Guizhou 563000, China
刊名: Chinese Herbal Medicines, 2017, Vol.9 (2), pp.176-182
来源数据库: Elsevier Journal
DOI: 10.1016/S1674-6384(17)60092-3
关键词: Anti-allergicChronic dermatitis-eczema24-dinitrochlorobenzeneSaxifrage cream
原始语种摘要: Abstract(#br)Objective(#br)Chronic dermatitis-eczema is a kind of inflammatory skin disease characterized by pruritic and eczematous skin lesions. In the present study, we investigated the anti-allergic effect of Saxifrage cream on eczema-like skin lesions induced by 2,4-dinitrochlorobenzene (DNCB) in mice.(#br)Methods(#br)KM mice were randomly divided into eight groups: normal group (Norm), model group (DNCB), positive group 1 (Dexamethasone cream, DEX), positive group 2 (Chinese herbal medicine Paeonol cream, PA), Saxifrage cream groups (equivalent to crude herb 1.25, 2.50, 5.00 g/g, S1, S2, S4), and negative group (Norm + S4). Except for the normal control group and negative control group, right ears of mice in other groups were repeatedly induced with 0.5% DNCB for four times for 3 d...
全文获取路径: Elsevier  (合作)

  • eczema 湿疹
  • induced 感应的
  • inflammatory 激怒的
  • dermatitis 皮炎
  • reduced 减缩的
  • significantly 较大地
  • sensitized 敏化的
  • pathological 病理学的
  • treated 加工的
  • group