Cerebrospinal fluid carnitine levels in patients with Parkinson's disease
作者: Félix Javier Jiménez-JiménezJuan Carlos RubioJosé Antonio MolinaMiguel Angel MartínYolanda CamposJulián Benito-LeónMiguel Ortí-ParejaTeresa GasallaJoaquín Arenas
作者单位: 1Department of Neurology, Hospital Universitario “Príncipe de Asturias”, Alcalá de Henares, Madrid, Spain
2Department of Biochemistry, Hospital Doce de Octubre, Madrid, Spain
3Department of Neurology, Hospital Doce de Octubre, Madrid, Spain
刊名: Journal of the Neurological Sciences, 1997, Vol.145 (2), pp.183-185
来源数据库: Elsevier Journal
DOI: 10.1016/S0022-510X(96)00259-6
关键词: Parkinson's diseaseOxidative stressCarnitineMitochondrial functionPlasmaCerebrospinal fluid
原始语种摘要: Abstract(#br)We assessed free carnitine (FC) and acyl-carnitine esters (AC) in both CSF and plasma from 29 patients with diagnostic criteria for PD, and from 29 healthy matched-controls. FC and AC levels in both CSF and plasma did not differ significantly between PD patients and controls, they were not influenced significantly by anti-parkinsonian drugs, and did not correlate with age at onset, duration and severity of PD. These results suggest that CSF carnitine levels are apparently unrelated with the risk for PD. © 1997 Elsevier Science B.V. All rights reserved.
全文获取路径: Elsevier  (合作)
影响因子:2.243 (2012)

  • carnitine 肉毒碱
  • parkinsonian 似帕金森氏病的
  • fluid 
  • controls 控制机构
  • plasma 深绿玉髓
  • apparently 显然地
  • CSF Central Switching Facility
  • matched 匹配的
  • significantly 较大地
  • suggest 建议