AKT-targeted anti-inflammatory activity of the methanol extract of Chrysanthemum indicum var. albescens
作者: Woo Seok YangDonghyun KimYoung-Su YiJi Hye KimHye Yoon JeongKyeonghwan HwangJong-Hoon KimJunseong ParkJae Youl Cho
作者单位: 1Department of Genetic Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea
2Department of Pharmaceutical Engineering, Cheongju University, Cheongju 28503, Republic of Korea
3Heritage Material Research Team, Amorepacific R&D Unit, Yongin 446-729, Republic of Korea
4Department of Physiology, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Republic of Korea
刊名: Journal of Ethnopharmacology, 2017, Vol.201 , pp.82-90
来源数据库: Elsevier Journal
DOI: 10.1016/j.jep.2017.03.001
关键词: Chrysanthemum indicum var. albescensNF-κBAKTAnti-inflammatory activityMacrophage
原始语种摘要: Abstract(#br)Ethnopharmacological relevance(#br)Wild chrysanthemum ( Chrysanthemum indicum ) is one of well-known medicinal plants traditionally used in Korea and China. As a variant of wild chrysanthemum, white wild chrysanthemum ( Chrysanthemum indicum var. albescens) is also ethnopharmacologically applied to treat various symptoms such as inflammatory diseases.(#br)Aim of study(#br)Although the anti-inflammatory activity of Chrysanthemum indicum has been reported, the anti-inflammatory activity and underlying molecular mechanism of white wild chrysanthemum are poorly understood.(#br)Materials and methods(#br)The effects of Chrysanthemum indicum var. albescens methanol extract (Civ-ME) on the production of inflammatory mediators, expression of pro-inflammatory genes, cell viability, and...
全文获取路径: Elsevier  (合作)
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影响因子:2.755 (2012)

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关键词翻译
关键词翻译
  • inflammatory 激怒的
  • chrysanthemum 菊花
  • extract 提取
  • targeted 对准目标的
  • luteolin 黄色素
  • luciferase 荧光素酶
  • medicinal 医学的
  • activity 活度
  • translocation 移位
  • nitric 氮的