Core–shell structured electrospun biomimetic composite nanofibers of calcium lactate/nylon-6 for tissue engineering
作者: Hem Raj PantPrabodh RisalChan Hee ParkLeonard D. TijingYeon Jun JeongCheol Sang Kim
作者单位: 1Department of Bio-nano System Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea
2Department of Engineering Science and Humanities, Pulchowk Campus, Tribhuvan University, Kathmandu, Nepal
3Department of Biochemistry, School of Medicine, Kathmandu University, Dhulikhel, Kavre, Nepal
4Department of Surgery, Chonbuk National University Medical School, Jeonju 516-712, Republic of Korea
5Division of Mechanical Design Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea
刊名: Chemical Engineering Journal, 2013, Vol.221 , pp.90-98
来源数据库: Elsevier Journal
DOI: 10.1016/j.cej.2013.01.072
关键词: ElectrospinningNylon-6Calcium lactateHybrid matsBiomaterials
英文摘要: Abstract(#br)In this work, core-shell structured nylon-6/lactic acid (LA) nanofibers have been produced via single-spinneret electrospinning from the simple blending of LA and nylon-6 solution. The low evaporation rate and plasticizer property of LA was found to be responsible for the formation of point-bonded morphology whereas solvent degradation of nylon-6 with complex phase separation mechanism could give spider-wave-like architecture of the mat and core–shell structure of the composite fibers. The core–shell nanostructure and existence of LA on the shell layer of the fiber were confirmed by TEM and XPS analysis. These fibers were further treated with calcium base to convert surface LA into calcium lactate (CL) which could increase the biocompatibility of composite mat. The SBF...
全文获取路径: Elsevier  (合作)
影响因子:3.473 (2012)

  • nylon 尼龙
  • shell 贝壳
  • Core 核心
  • Nylon 耐纶
  • lactate 乳酸盐
  • composite 复合的
  • engineering 工程
  • calcium 
  • tissue 组织