MiR-210: A potential therapeutic target against radiation-induced enteropathy
作者: Saad HamamaMuhammad Zaeem NomanPascal GervazSylvie DelanianMarie-Catherine Vozenin
作者单位: 1INSERM U-1030 “Molecular Radiotherapy”, Institut Gustave Roussy, Villejuif, France
2LabEX LERMIT Villejuif, France
3Université Paris Sud Paris XI, Le Kremlin Bicêtre, France
4INSERM, U753, Laboratoire d’immunologie des Tumeurs Humaines: Interaction Effecteurs Cytotoxiques-Système Tumoral, Institut Gustave-Roussy, Villejuif, France
5Geneva University Hospital and Medical School, Geneva, Switzerland
6Unité de Radiopathologie, Service Oncologie-Radiothérapie, Hôpital Saint-Louis, APHP, Paris, France
7Laboratoire de RadioOncologie, Swiss Cancer Center of Lausanne, CHUV, Lausanne, Switzerland
刊名: Radiotherapy and Oncology, 2014, Vol.111 (2), pp.219-221
来源数据库: Elsevier Journal
DOI: 10.1016/j.radonc.2013.10.030
关键词: Anti-fibrotic treatmentRadiation-induced fibrosisRadiation enteropathymicroRNA miR-210TroloxPentoxifylline
英文摘要: Abstract(#br)A previously undescribed and robust miR210 overexpression is shown in intestinal samples obtained from patients with radiation enteropathy and fibrotic cultured cells. In addition, miR-210 overexpression is repressed by antifibrotic treatment combining pentoxifylline and α-tocopherol.
全文获取路径: Elsevier  (合作)
影响因子:4.52 (2012)

  • induced 感应的
  • enteropathy 肠病
  • potential 
  • against 反对
  • therapeutic 治疗的
  • target 目标
  • radiation 辐射
  • fibrotic 纤维变性的
  • fibrosis 纤维化
  • treatment 处理