Two new eupodienone lignans from Gymnotheca chinensis
作者: Shi-Ji XiaoFang ChenLi-Sheng DingYan Zhou
作者单位: 1Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
2College of Life Science, Sichuan University, Chengdu 610064, China
刊名: Chinese Chemical Letters, 2014, Vol.25 (3), pp.463-464
来源数据库: Elsevier Journal
DOI: 10.1016/j.cclet.2013.11.053
关键词: Gymnotheca chinensisSaururaceaeEupodienoneLignan
原始语种摘要: Abstract(#br)Two new eupodienone lignans, named gymnothelignan T ( 1 ) and gymnothelignan U ( 2 ) were isolated from the whole plants of endemic medicinal plant of Gymnotheca chinensis (Saururaceae). The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound 1 was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC 50 values above 50μmol/L.
全文获取路径: Elsevier  (合作)
影响因子:1.21 (2012)

  • 活度 已试验的
  • lignans 木脂素类
  • endemic 地方病
  • medicinal 医学的
  • lines 线型
  • appreciable 明显的
  • values 价值观
  • above 在上面
  • tested 已试验的
  • activity 已试验的
  • cytotoxic 细胞毒素的