Adjuvant Radiotherapy Versus Wait-and-See After Radical Prostatectomy: 10-year Follow-up of the ARO 96–02/AUO AP 09/95 Trial
作者: Thomas WiegelDetlef BartkowiakDirk BottkeClaudia BronnerUrsula SteinerAlessandra SiegmannReinhard GolzStephan StörkelNormann WillichAxel SemjonowMichael StöckleChristian RübeUdo RebmannTilman KälbleHorst Jürgen FeldmannManfred WirthRainer HofmannRita Engenhart-CabillicAxel HinkeWolfgang HinkelbeinKurt Miller
作者单位: 1Department of Radiation Oncology, University Hospital Ulm, Ulm, Germany
2Department of Urology, Charité Universitätsmedizin, Campus Benjamin- Franklin, Berlin, Germany
3Department of Radiation Oncology, Charité Universitätsmedizin, Campus Benjamin- Franklin, Berlin, Germany
4Department of Pathology, Helios-Clinic Wuppertal, Wuppertal, Germany
5Department of Radiation Oncology, University Hospital Münster, Münster, Germany
6Department of Urology, University Hospital Münster, Münster, Germany
7Department of Urology, University Hospital Homburg/Saar, Homburg, Germany
8Department of Radiation Oncology, University Hospital Homburg/Saar, Homburg, Germany
9Department of Urology, Diakonissen-Krankenhaus Dessau, Dessau-Rosslau, Germany
10Department of Urology, General Hospital Fulda, Fulda, Germany
11Department of Radiation Oncology, General Hospital Fulda, Fulda, Germany
12Department of Urology, University Hospital Dresden, Dresden, Germany
13Departments of Urology, University Hospital Giessen-Marburg, Marburg, Germany
14Department of Radiation Oncology, University Hospital Giessen-Marburg, Marburg, Germany
15WiSP GmbH, Langenfeld, Germany
刊名: European Urology, 2014, Vol.66 (2), pp.243-250
来源数据库: Elsevier Journal
DOI: 10.1016/j.eururo.2014.03.011
关键词: Adjuvant radiotherapyProstate cancerProstate-specific antigenRadical prostatectomyWait-and-see
原始语种摘要: Abstract(#br)Background(#br)Local failure after radical prostatectomy (RP) is common in patients with cancer extending beyond the capsule. Three prospectively randomized trials demonstrated an advantage for adjuvant radiotherapy (ART) compared with a wait-and-see (WS) policy.(#br)Objective(#br)To determine the efficiency of ART after a 10-yr follow-up in the ARO 96–02 study.(#br)Design, setting, and participants(#br)After RP, 388 patients with pT3 pN0 prostate cancer (PCa) were randomized to WS or three-dimensional conformal ART with 60Gy. The present analysis focuses on intent-to-treat patients who achieved an undetectable prostate-specific antigen after RP (ITT2 population)—that is, 159 WS plus 148 ART men.(#br)Outcome measurements and statistical analysis(#br)The...
全文获取路径: Elsevier  (合作)
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影响因子:10.476 (2012)

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关键词翻译
关键词翻译
  • follow 
  • prostatectomy 前列腺切除术
  • achieved 获得的
  • point 
  • grade 品位
  • efficiency 效率
  • ratio 
  • survival 生存
  • radiotherapy 放射线疗法
  • analysis 分析