Influence of selected angiotensin-converting enzyme inhibitors on alloxan-induced diabetic cataract in rabbits
作者: Anna JabłeckaEwa CzaplickaJan OlszewskiPaweł BogdańskiHanna KraussIwona SmolarekNatasza BalcerAnna SkołudaArtur Cieślewicz
作者单位: 1Department of Clinical Pharmacology, University of Medical Sciences, Długa 1/2, 61-848 Poznań, Poland
2;Department of Ophthalmology, University of Medical Sciences, Długa 1/2, 61-848 Poznań, Poland
3;Department of Internal Medicine, Metabolic Disorders, and Hypertension, University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznań, Poland
4;Department of Physiology, University of Medical Sciences, Święcickiego 6, 60-781 Poznań, Poland
刊名: Pharmacological Reports, 2010, Vol.62 , pp.80-80
来源数据库: Elsevier Journal
DOI: 10.1016/S1734-1140(10)71192-0
关键词: Cataractdiabetesangiotensin-converting enzyme inhibitorsSH-group
原始语种摘要: Background(#br)Hyperglycemia enhances cataractogenesis. Elevated glucose level is commonly accompanied by arterial hypertension, for which angio-tensin-converting enzyme (ACE) inhibitors (ACEIs) are a widely used intervention. ACE inhibitors exert some endothelial pleiotropic actions and can beneficially modulate glucose control and some other metabolic pathways.(#br)The aim(#br)The aim of this study was to evaluate the effect of ACEIs on cataract formation in experimental alloxan-induced diabetes in rabbits and assess the role of the reactive function group of the ACEIs in this process.(#br)Material and Methods(#br)Two study and two control groups of rabbits were examined. In the study groups and in one of the control groups, diabetes was induced by alloxan. The study groups were...
全文获取路径: Elsevier  (合作)
影响因子:1.965 (2012)

  • converting 转换
  • angiotensin 血管紧张肽
  • diabetic 糖尿病患者
  • alloxan 阿脲
  • cataract 急流
  • induced 感应的
  • diabetes 糖尿病
  • ACE Acceptance Checkout Equipment
  • enzyme 
  • glucose 葡萄糖