Low mannose-binding lectin (MBL) levels and MBL genetic polymorphisms associated with the risk of neonatal sepsis: An updated meta-analysis
作者: Jun LuoFen XuGuang-Jin LuHung-Chih LinZhi-Chun Feng
作者单位: 1Department of Neonatology, BaYi Children's Hospital Affiliated to Clinical Medical College in Beijing Military General Hospital of Southern Medical University, Beijing, China
2Department of Neonatology, Bao'an Maternity and Child Health Hospital of Shenzhen, Guangdong, China
3Department of Pediatrics and School of Chinese Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan
刊名: Early Human Development, 2014, Vol.90 (10), pp.557-564
来源数据库: Elsevier Journal
DOI: 10.1016/j.earlhumdev.2014.07.007
关键词: Mannose-binding lectinPolymorphismNeonatal sepsisMeta-analysis
原始语种摘要: Abstract(#br)Background(#br)Relatively low serum mannose-binding lectin (MBL) levels and MBL genetic polymorphisms have been implicated as high risk factors for neonatal sepsis. However, different studies have reported conflicting findings and have generally been underpowered to exclude modest effect sizes.(#br)Methods(#br)Standard methodology of systematic reviews and meta-analyses was followed. PubMed, Embase, Cochrane, Web of Science, and Scopus databases were searched from January 1996 to December 2013. The eligible studies were collected and analyzed using Review Manager 5.2. Meta-Disc version 1.4 was used to describe and calculate sensitivity, specificity, summary receiver operator characteristic (SROC) curves and area under the curve. SROC curve analysis was used to summarize the...
全文获取路径: Elsevier  (合作)
影响因子:2.02 (2012)

  • 动力不足 相关的
  • neonatal 新生儿的
  • sepsis 败血症
  • mannose 甘露糖
  • analysis 分析
  • genetic 遗传的
  • binding 装订
  • lectin 植物凝血素
  • confidence 信用
  • associated 相关的
  • underpowered 相关的