Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginseng
作者: Kwang-Soo BaekYong Deog HongYong KimNak Yoon SungSungjae YangKyoung Min LeeJoo Yong ParkJun Seong ParkHo Sik RhoSong Seok ShinJae Youl Cho
作者单位: 1Department of Genetic Engineering, Sungkyunkwan University, Suwon, Korea
2Skin Research Institute, AmorePacific R&D Center, Yongin, Korea
刊名: Journal of Ginseng Research, 2015, Vol.39 (2), pp.155-161
来源数据库: Elsevier Journal
DOI: 10.1016/j.jgr.2014.10.004
关键词: anti-inflammatory activityAP-SFc-JunKorean ginsengPanax ginseng Meyer
英文摘要: Abstract(#br)Background(#br)Korean ginseng is an ethnopharmacologically valuable herbal plant with various biological properties including anticancer, antiatherosclerosis, antidiabetic, and anti-inflammatory activities. Since there is currently no drug or therapeutic remedy derived from Korean ginseng, we developed a ginsenoside-enriched fraction (AP-SF) for prevention of various inflammatory symptoms.(#br)Methods(#br)The anti-inflammatory efficacy of AP-SF was tested under in vitro inflammatory conditions including nitric oxide (NO) production and inflammatory gene expression. The molecular events of inflammatory responses were explored by immunoblot analysis.(#br)Results(#br)AP-SF led to a significant suppression of NO production compared with a conventional Korean ginseng saponin...
全文获取路径: Elsevier  (合作)
影响因子:2.259 (2012)

  • ginsenoside 人参皂甙
  • ginseng 人参
  • inflammatory 激怒的
  • fraction 分数
  • activity 活度
  • enriched 浓缩
  • Korean 朝鲜