Importance of Direct Antiglobulin Test (DAT) in Cord Blood: Causes of DAT (+) in a Cohort Study
作者: Serena ValsamiMarianna PolitouΤheodora BoutsikouDespina BrianaMilena PapatestaAriadne Malamitsi-Puchner
作者单位: 1Blood Transfusion Department, Aretaieion Hospital, Athens University Medical School, Athens, Greece
2Neonatal Division, 2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University, Medical School, Athens, Greece
刊名: Pediatrics & Neonatology, 2015, Vol.56 (4), pp.256-260
来源数据库: Elsevier Journal
DOI: 10.1016/j.pedneo.2014.11.005
关键词: ABO incompatibilitydirect antiglobulin test (DAT)hyperbilirubinemiamaternal alloimmunizationphototherapy
英文摘要: Background(#br)The direct antiglobulin test (DAT) is the cornerstone of the diagnosis of hemolytic disease of the newborn (HDN). The aim of this study was to review the incidence and causes of positive DAT in cord blood in relation to development of HDN.(#br)Methods(#br)We retrospectively reviewed all results of DAT, which is routinely performed in cord blood samples, along with the laboratory and infants' medical records.(#br)Results(#br)DAT was positive in 70/2695 (2.59%) cases. In 64/70 (91.43%) cases, DAT positivity was attributed to ABO incompatibility. There were 50/218 (22.93%) DAT (+) cases in the A/O group and 13/97 (13.40%) cases in the B/O group ( p = 0.0664). Two DAT (+) cases were attributed to maternal alloimmunization (anti-Fya and anti-JKb, respectively), and one to...
全文获取路径: Elsevier  (合作)
影响因子:0.932 (2012)