Detection of Hyaluronic Acid Receptor in Human Vocal Folds by immunohistochemistry
作者: Luiz Henrique Fonseca BarbosaHugo Valter Lisboa RamosLuciano Rodrigues NevesNoemi Grigoletto de BiaseCelina OshimaJosé Eduardo de Sá PedrosoPaulo Augusto de Lima Pontes
作者单位: 1Master's degree in science, ENT Department, UNIFESP-EPM; adjunct professor of ENT, UFBA
2Master's degree in science, ENT Department, UNIFESP-EPM; doctoral student, ENT Department, UNIFESP-EPM
3Doctor in medicine, ENT Department, UNIFESP-EPM; teaching professor in the ENT Department post-graduate course, UNIFESP-EPM
4Doctor in medicine, Pathology Department, UNIFESP-EPM; teaching professor in the molecular pathology sector, Pathology Department UNIFESP-EPM
5Doctor in medicine, ENT Department, UNIFESP-EPM; coordinaor of the laryngology and voice sector, ENT Department, UNIFESP-EPM
6Full professor, ENT Department, UNIFESP; head of the ENT Department, UNIFESP. Otorhinolaryngology and Head & Neck Surgery Department, Sao Paulo Federal University - Paulista Medical School
刊名: Brazilian Journal of Otorhinolaryngology, 2008, Vol.74 (2), pp.201-206
来源数据库: Elsevier Journal
DOI: 10.1016/S1808-8694(15)31089-2
关键词: immunohistochemistrylarynxvocal foldhyaluronic acid
原始语种摘要: Summary(#br)Hyaluronic acid receptor is a glycoprotein of the plasmatic membrane, and the CD44 is its representative, expressed in many cell types where it has the task of cell adhesion.(#br)Aim(#br)the goal of the present experimental study is to investigate the possibility of using immunohistochemistry to identify the distribution of hyaluronic acid along the vocal fold.(#br)Materials and Methods(#br)We resected the normal vocal folds from a normal 23 year-old male black individual. The slides were analyzed by means of a histomorphometric study, comparing the color intensity in the superficial, middle and deep layers of the lamina propria. In the silanized slides we used immunohistochemistry, and evaluated the slides under light microscopy with 40x magnification, and the color changed...
全文获取路径: Elsevier  (合作)
影响因子:0.545 (2012)

  • vocal 声音的
  • superficial 表面的
  • silanized 硅烷化过的
  • glycoprotein 糖蛋白
  • slides 幻灯片
  • central 中心的
  • findings 结论
  • color 上色
  • adhesion 粘附
  • magnification 放大