Tremor in multiple sclerosis: The intriguing role of the cerebellum
作者: Samar S. AyacheMoussa A. ChalahTarik Al-AniWassim H. FarhatHela G. ZouariAlain CréangeJean-Pascal Lefaucheur
作者单位: 1Faculté de Médecine de Créteil, Université Paris Est Créteil, EA 4391, Créteil, France
2Hôpital Henri-Mondor, AP-HP, Service de Physiologie, Explorations Fonctionnelles, Créteil, France
3Université de Versailles Saint-Quentin-en-Yvelines, Laboratoire d'Ingénierie des Systèmes de Versailles, Vélizy, France
4École Supérieure d'Ingénieurs en Électronique et Électrotechnique de Paris, Département Informatique et Télécommunication, Noisy-Le-Grand, France
5Hôpital Henri-Mondor, AP-HP, Service de Neurologie, Créteil, France
刊名: Journal of the Neurological Sciences, 2015, Vol.358 (1-2), pp.351-356
来源数据库: Elsevier Journal
DOI: 10.1016/j.jns.2015.09.360
关键词: AtaxiaBrainstem reflexesCerebellar signsCerebello-thalamo-cortical inhibitionElectromyographyNeurophysiologyTranscranial magnetic stimulation
原始语种摘要: Abstract(#br)Tremor is frequently encountered in multiple sclerosis (MS) patients. However, its underlying pathophysiological mechanisms remain poorly understood. Our aim was to assess the potential role of the cerebellum and brainstem structures in the generation of MS tremor. We performed accelerometric (ACC) and electromyographic (EMG) assessment of tremor in 32 MS patients with manual clumsiness. In addition to clinical examination, patients underwent a neurophysiological exploration of the brainstem and cerebellar functions, which consisted of blink and masseter inhibitory reflexes, cerebello-thalamo-cortical inhibition (CTCi), and somatosensory evoked potentials. Tremor was clinically visible in 18 patients and absent in 14. Patients with visible tremor had more severe score of...
全文获取路径: Elsevier  (合作)
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影响因子:2.243 (2012)

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关键词翻译
关键词翻译
  • sclerosis 硬化
  • cerebellum 小脑
  • tremor 震动
  • evoked 诱发的
  • clinically 临床上
  • multiple 多次的
  • potential 
  • cerebellar 小脑的
  • somatosensory 躯体感觉
  • visible 看得见的