Cord blood copeptin concentrations in fetal macrosomia
作者: Despina D. BrianaStavroula BakaMaria BoutsikouTheodora BoutsikouMarieta XagorariDimitrios GourgiotisAriadne Malamitsi-Puchner
作者单位: 1Department of Neonatology, Athens University Medical School, Athens, Greece
2Laboratory of Clinical Biochemistry-Molecular Diagnostics, 2nd Department of Pediatrics, Athens University Medical School, Athens, Greece
刊名: Metabolism, 2016, Vol.65 (1), pp.89-94
来源数据库: Elsevier Journal
DOI: 10.1016/j.metabol.2015.09.018
关键词: CopeptinAVPInsulinCord bloodFetal macrosomia
原始语种摘要: Abstract(#br)Background/aim(#br)Excessive fetal growth is associated with increased adiposity and reduced insulin sensitivity at birth. Copeptin, a surrogate marker of arginine vasopressin (AVP) secretion, is upregulated in states of hyperinsulinemia and is considered one of the mediators of insulin resistance. We aimed to investigate cord blood concentrations of copeptin (C-terminal fragment of AVP pro-hormone) in healthy large-for-gestational-age (LGA) infants at term.(#br)Methods(#br)This prospective study was conducted on 30 LGA (n=30) and 20 appropriate-for-gestational-age (AGA, n=20) singleton full-term healthy infants. Cord blood copeptin and insulin concentrations were determined by ELISA and IRMA,...
全文获取路径: Elsevier  (合作)
影响因子:3.096 (2012)

  • blood 血液
  • fetal 胎的
  • concentrations 浓聚物
  • macrosomia 巨大症
  • insulin 胰岛素
  • gestational 妊娠期的
  • adiposity 肥胖
  • cesarean 剖腹产术的
  • hormone 激素
  • increased 增加