The regulatory mechanism of Eucommia ulmoides flavone effects on damage repair in enterocytes
作者: Tarique HussainBie TanGang LiuWekai RenNajma RahuYulong YinDildar Hussain KalhoroMuhammad Saleem Kalhoro
作者单位: 1National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Hunan, China
2University of the Chinese Academy of Sciences, Beijing, China
3Animal Sciences Division, Nuclear Institute for Agriculture and Biology (NIAB), Pakistan
4Affiliation is missing
刊名: Free Radical Biology and Medicine, 2018, Vol.120 , pp.S139-S140
来源数据库: Elsevier Journal
DOI: 10.1016/j.freeradbiomed.2018.04.460
原始语种摘要: Eucommia ulmoids (EU) is a Chinese herbal plant grown on a large scale basis and exerts an array of medicinal properties. The aim of this study was to promote natural bioactive compounds derived from EU flavone which possess anti-oxidative properties on damage repair in enterocytes. IPEC-J2 cells were cultured in DMEM-H medium based on two treatments including 10μg/mL EUF+40 ng/mL, LPS and 10μg/mL EUF+40 ng/mL LPS+10 μmol/L LY29400(PI3K inhibitor) for 2 days. The results showed that EU flavone+LY29400 treated group significantly decreased cell viability, proliferation (P0.05). The SOD activity and putrescine, spermidine and spermine concentrations were reduced (P0.05). The Western blotting showed that that EU flavone+LY29400 treated cells decreased...
全文获取路径: Elsevier  (合作)
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影响因子:5.271 (2012)

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关键词翻译
关键词翻译
  • flavone 黄酮
  • regulatory 控制的
  • mechanism 机构
  • damage 损伤
  • medicinal 医学的
  • treated 加工的
  • intervention 
  • blotting 浸透
  • repair 修理
  • SOD Superintendent Of Documents