Statin therapy reduces contrast-induced nephropathy: An analysis of contemporary percutaneous interventions
作者: Sanjaya KhanalNizar AttallahDean E. SmithEva Kline-RogersDavid ShareMichael J. O’DonnellMauro Moscucci
作者单位: 1Henry Ford Heart and Vascular Institute, Detroit, Mich
2Henry Ford Hospital, Detroit, Mich
3University of Michigan, Ann Arbor, Mich
4Blue Cross Blue Shield of Michigan, Detroit
5St. Joseph Mercy Hospital, Ann Arbor, Mich
刊名: The American Journal of Medicine, 2005, Vol.118 (8), pp.843-849
来源数据库: Elsevier Journal
DOI: 10.1016/j.amjmed.2005.03.031
关键词: KidneyAngioplastyContrast mediaLipidsContrast nephropathy
原始语种摘要: Abstract(#br)Purpose(#br)We sought to examine whether statin therapy before percutaneous coronary intervention results in reduction in contrast-induced nephropathy (CIN). Intravascular administration of contrast media can have nephrotoxic effects, particularly in patients with baseline renal insufficiency. Along with lowering serum cholesterol, statins have pleiotropic effects in the vasculature. The effect of statin use on CIN is unknown.(#br)Subjects and methods(#br)We studied 29409 patients who had both baseline preprocedure and peak postprocedure serum creatinine measured at the time of their percutaneous coronary intervention (PCI). Baseline demographics and creatinine profile before and after the procedure were compared between patients who received preprocedure...
全文获取路径: Elsevier  (合作)
影响因子:4.768 (2012)

  • nephropathy 肾病
  • percutaneous 经皮的
  • intervention 
  • induced 感应的
  • contrast 差异
  • CIN Carrier INput
  • cholesterol 胆甾醇
  • contemporary 流行
  • coronary 冠状的
  • associated 相关的