Synthesis, chemiluminescence, and application of 2,4-disubstituted phenyl 10-methyl-10λ 4 -acridine-9-carboxylates
作者: Manabu NakazonoShinkoh NanbuTakeyuki AkitaKenji Hamase
作者单位: 1Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan
2Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo, 102-8554, Japan
刊名: Dyes and Pigments, 2019, Vol.170
来源数据库: Elsevier Journal
DOI: 10.1016/j.dyepig.2019.107628
关键词: ChemiluminescenceAcridinium esterElectron-withdrawing groupNeutral conditionCholine
英文摘要: Abstract(#br)2,4-Disubstituted phenyl 10-methyl-10λ 4 -acridine-9-carboxylate derivatives were synthesized and the chemiluminescence of each was measured at pH 6–9. The introduction of electron-withdrawing groups at 2,4-positions in the phenyl moiety intensified chemiluminescence. 2,4-(Dimethoxycarbonyl)phenyl 10-methyl-10λ 4 -acridine-9-carboxylate trifluoromethanesulfonate salt produced long-lasting chemiluminescence emission, showed maximum chemiluminescence intensities at pH 8 and was used in simple chemiluminescence assays of hydrogen peroxide and choline under neutral conditions. The linear calibration range and detection limit of choline at pH 8 were 0.1–1000 μM and 0.01 μM, respectively.
全文获取路径: Elsevier  (合作)
影响因子:3.532 (2012)

  • disubstituted 二基取代的
  • phenyl 苯基
  • acridine 吖啶
  • methyl 甲基
  • application 申请