Contemporary Use and Effectiveness of N -Acetylcysteine in Preventing Contrast-Induced Nephropathy Among Patients Undergoing Percutaneous Coronary Intervention
作者: Hitinder S. GurmDean E. SmithOtavio BerwangerDavid ShareTheodore SchreiberMauro MoscucciBrahmajee K. Nallamothu
作者单位: 1Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
2Research Institute-Cardiac Hospital (HCor), Sao Paulo-SP, Brazil
3Division of Family Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
4Detroit Medical Center-Cardiovascular Institute, Detroit, Michigan
5Cardiovascular Division, University of Miami Medical Center, Miami, Florida
刊名: JACC: Cardiovascular Interventions, 2012, Vol.5 (1), pp.98-104
来源数据库: Elsevier Journal
DOI: 10.1016/j.jcin.2011.09.019
关键词: contrast-induced nephropathyN -acetylcysteinepercutaneous coronary intervention
原始语种摘要: Objectives(#br)The aim of this study was to examine the use of and outcomes associated with use of N -acetylcysteine (NAC) in real-world practice.(#br)Background(#br)The role of NAC in the prevention of contrast-induced nephropathy (CIN) is controversial, leading to widely varying recommendations for its use.(#br)Methods(#br)Use of NAC was assessed in consecutive patients undergoing nonemergent percutaneous coronary intervention from 2006 to 2009 in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium, a large multicenter quality improvement collaborative. We examined the overall prevalence of NAC use in these patients and then used propensity matching to link its use with clinical outcomes, including CIN, nephropathy-requiring dialysis, and death.(#br)Results(#br)Of the...
全文获取路径: Elsevier  (合作)
影响因子:6.552 (2012)

  • nephropathy 肾病
  • acetylcysteine 乙酰半胱胺酸
  • intervention 
  • coronary 冠状的
  • induced 感应的
  • CIN Carrier INput
  • dialysis 透析
  • percutaneous 经皮的
  • insufficiency 机能不全
  • associated 相关的