Clinicopathological manifestations of myocarditis in a heart failure population
作者: Louis Maximilian BujaGiulia OttavianiMilica IlicBihong ZhaoLaura C. LelenwaAna Maria SeguraYu BaiAlice ChenBindu AkkantiRahat HussainSriram NathanMarija PetrovicRajko RadovancevicIgor D. GregoricBiswajit Kar
作者单位: 1Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA
2Cardiovascular Pathology Research Laboratory, Texas Heart Institute, CHI St. Luke's Hospital, Houston, TX, USA
3Lino Rossi Research Center, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy
4Center for Advanced Heart Failure, Cardiopulmonary Support and Transplantation Program, Memorial Hermann Heart & Vascular Institute, Memorial Hermann Hospital – Texas Medical Center, Houston, TX, USA
刊名: Cardiovascular Pathology, 2020, Vol.45
来源数据库: Elsevier Journal
DOI: 10.1016/j.carpath.2019.107190
关键词: MyocarditisHeart failureEndomyocardial biopsyOrthotopic heart transplantation
英文摘要: Abstract(#br)Myocarditis continues to present challenges in diagnosis and management. The goal of this study is to determine the occurrence and manifestations of myocarditis in a heart failure (HF) population. The analyzed patients had acute or persistent HF and were referred over a 6-year period to a quaternary HF center for advanced HF therapies including mechanical circulatory support, left ventricular assist device (LVAD) implantation, and/or heart transplantation. The histopathological diagnosis of myocarditis was made based on the presence of an inflammatory infiltrate of the myocardium, typically with associated cardiomyocyte (CMC) damage, combined as indicated with immunohistochemical and molecular biology characterization. The pathological findings were correlated with a panel of...
全文获取路径: Elsevier  (合作)
影响因子:2.352 (2012)

  • myocarditis 心肌炎
  • failure 破坏
  • heart 心脏
  • population 母体