Advancing Age and the Odds of Upgrading and Upstaging at Radical Prostatectomy in Men with Gleason Score 6 Prostate Cancer
作者: Jonathan E. LeemanMing-Hui ChenHartwig HulandMarkus GraefenAnthony V. D’AmicoDerya Tilki
作者单位: 1Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women’s Hospital, Boston, MA
2Department of Statistics, University of Connecticut, Storrs, CT
3Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Eppendorf, Germany
4Department of Urology, University Hospital Hamburg-Eppendorf, Eppendorf, Germany
刊名: Clinical Genitourinary Cancer, 2019, Vol.17 (6), pp.e1116-e1121
来源数据库: Elsevier Journal
DOI: 10.1016/j.clgc.2019.07.018
关键词: Active surveillanceMpMRI
英文摘要: Abstract(#br)Purpose(#br)To identify a subset of men with Gleason score (GS) 6 prostate cancer who are at high risk for upgrading/upstaging who should be recommended for multiparametric magnetic resonance imaging.(#br)Patients and Methods(#br)Between 1992 and 2017, a total of 3571 men with GS6 prostate cancer were consecutively treated at a single institution with radical prostatectomy. Logistic regression multivariable analyses to determine the odds of upgrading and upstaging were performed, adjusting for age and year of diagnosis, clinical T category, prostate-specific antigen level, number of biopsy cores, and percentage of positive biopsy cores.(#br)Results(#br)Of 3571 men, the disease of 115 (3.22%), 245 (6.86%), and 254 (7.11%) was upgraded, was upstaged, or had positive surgical...
全文获取路径: Elsevier  (合作)
影响因子:1.429 (2012)

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