Increased plasma sestrin2 concentrations in patients with chronic heart failure and predicted the occurrence of major adverse cardiac events: A 36-month follow-up cohort study
作者: Haixiong WangNa LiXin ShaoJun LiLiping GuoXingyan YuYuehui SunJinlin HaoHuaimin NiuJie XiangXiaofang LiXuebin Han
作者单位: 1Department of Cardiology, Shanxi Cardiovascular Hospital, Taiyuan, Shanxi, China
2Department of geriatric medicine,Shanxi Dayi Hospital, Taiyuan, Shanxi, China
刊名: Clinica Chimica Acta, 2019, Vol.495 , pp.338-344
来源数据库: Elsevier Journal
DOI: 10.1016/j.cca.2019.04.084
关键词: Chronic heart failureSestrin2Major adverse cardiac eventsPrognosis
原始语种摘要: Abstract(#br)Background(#br)Previous study had demonstrated that sestrin2 (Sesn2) expression was increased in human failing heart. Although, the circulating Sesn2 concentrations in patients with chronic heart failure (CHF) remains unknown. This study investigated plasma Sesn2 concentrations in patients with CHF and the role between Sesn2 and the occurrence of major adverse cardiac events.(#br)Methods(#br)A total of 80 control subjects and 220 CHF patients were enrolled and the Sesn2 concentrations of each sample were measured. Additionally, the occurrence of major adverse cardiac events in each CHF patient were followed prospectively for 36 months.(#br)Results(#br)Increased plasma Sesn2 concentrations were found in CHF patients and gradually increased from New York Heart Association...
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:2.85 (2012)

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关键词翻译
关键词翻译
  • events 定时
  • adverse 逆的
  • cohort 伙伴
  • cardiac 贲门
  • heart 心脏
  • concentrations 浓聚物
  • plasma 深绿玉髓
  • failure 破坏
  • chronic 延续很长的
  • occurrence 事件