The changing definition of contrast-induced nephropathy and its clinical implications: Insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2)
作者: Nicklaus K. SlocumP. Michael GrossmanMauro MoscucciDean E. SmithHerbert D. AronowSimon R. DixonDavid ShareHitinder S. Gurm
作者单位: 1University of Michigan School of Medicine, Ann Arbor, MI
2University of Miami, Miami, FL
3St JosephMercyHospital, Ann Arbor, MI
4William Beaumont Hospital, Royal Oak, MI
5Department of Family Medicine, University of Michigan, Ann Arbor, MI
刊名: American Heart Journal, 2012, Vol.163 (5), pp.829-834
来源数据库: Elsevier Journal
DOI: 10.1016/j.ahj.2012.02.011
原始语种摘要: Background(#br)The traditional definition of contrast-induced nephropathy (CIN) has been an absolute rise of serum creatinine (Cr) of ≥0.5 mg/dL, although most recent clinical trials have included a ≥25% increase from baseline Cr. The clinical implication of this definition change remains unknown.(#br)Methods and Results(#br)We compared the association of the two definitions with risk of death or need for dialysis among 58,957 patients undergoing percutaneous coronary intervention in 2007 to 2008 in a large collaborative registry. Patients with a preexisting history of renal failure requiring dialysis were excluded. Contrast-induced nephropathy as defined by a rise in Cr ≥0.5 mg/dL (CIN Traditional ) developed in 1,601, whereas CIN defined either as Cr ≥0.5 mg/dL or ≥25% increase in...
全文获取路径: Elsevier  (合作)
影响因子:4.497 (2012)

  • CIN Carrier INput
  • nephropathy 肾病
  • definition 清晰度
  • induced 感应的
  • dialysis 透析
  • renal 肾的
  • developed 开发
  • abnormal 异常的
  • intervention 
  • contrast 差异