The effect of obesity on pathological complete response and survival in breast cancer patients receiving uncapped doses of neoadjuvant anthracycline-taxane-based chemotherapy
作者: Alex FarrMyriam StolzLukas BaumannZsuzsanna Bago-HorvathElisabeth OppolzerGeorg PfeilerMichael SeifertChristian F. Singer
作者单位: 1Department of Obstetrics and Gynecology, Division of Gynecology and Gynecologic Oncology, Breast Health Center, Medical University of Vienna, Vienna, Austria
2Section for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria
3Clinical Institute for Pathology, Medical University of Vienna, Vienna, Austria
刊名: The Breast, 2017, Vol.33 , pp.153-158
来源数据库: Elsevier Journal
DOI: 10.1016/j.breast.2017.04.001
关键词: Breast cancerChemotherapyObesityOutcomePathological complete responseSurvival
原始语种摘要: Abstract(#br)Purpose(#br)The effect of obesity in breast cancer patients undergoing neoadjuvant chemotherapy (NAC) remains controversial. The aim of this study was to determine the obesity-related effect on pathological complete response (pCR) and survival in women receiving full uncapped doses of NAC.(#br)Methods(#br)We retrospectively analyzed the data of all consecutive women who underwent anthracycline-taxane-based NAC for primary breast cancer between 2005 and 2015 at the Department of Obstetrics and Gynecology, Medical University of Vienna. Following the WHO criteria, women with a body mass index (BMI) ≥30 kg/m 2 at baseline were considered obese, whereas those with a BMI <30 kg/m 2 were considered non-obese. Those with dose reductions or dose capping were not eligible for study...
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:2.491 (2011)

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关键词翻译
关键词翻译
  • chemotherapy 化学疗法
  • pathological 病理学的
  • uncapped 无限的
  • breast 胸部
  • survival 生存
  • receiving 接收
  • cancer 癌症
  • effect 效应
  • response 响应
  • complete 实行