Impact of Adherence to Multidisciplinary Recommendations for Adjuvant Treatment in Radical Prostatectomy Patients With High Risk of Recurrence
作者: Sophie KnipperMaryam Sadat-KhonsariKatharina BoehmPhilipp MandelLars BudäusThomas SteuberTobias MaurerHans HeinzerRudolf SchwarzGuido SauterDerya TilkiHartwig HulandMarkus Graefen
作者单位: 1Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany
2Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada
3Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany
4Department of Urology, University Hospital Mainz, Mainz, Germany
5Department of Urology, University Hospital Frankfurt, Frankfurt, Germany
6Department of Radiation Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany
7Department of Pathology, University Hospital Hamburg-Eppendorf, Hamburg, Germany
刊名: Clinical Genitourinary Cancer, 2020, Vol.18 (2), pp.e112-e121
来源数据库: Elsevier Journal
DOI: 10.1016/j.clgc.2019.09.007
关键词: Adjuvant radiationMultidisciplinary assessmentOncological outcomesProstate cancerRadiation recommendation
英文摘要: Abstract(#br)Introduction(#br)The purpose of this study was to investigate adherence to recommended adjuvant radiotherapy (aRT) in radical prostatectomy (RP) patients with adverse pathologic features and to analyse the outcome of patients who followed or denied this recommendation.(#br)Patients and Methods(#br)We included 1140 consecutive RP patients (2006-2015) with non-organ confined (pT3) prostate cancer and either positive surgical margins (R1) and/or lymph node involvement (pN1) and non-detectable postoperative prostate-specific antigen who received multidisciplinary aRT recommendations. Patients were stratified into adherence versus non-adherence to recommendations. Additionally, subgroups within pathologic criteria (pT3R1N0, pT3R0N1, pT3R1N1) were analyzed. Kaplan-Meier, as well as...
全文获取路径: Elsevier  (合作)
影响因子:1.429 (2012)