Adolescent anorexia nervosa: Cross-sectional and follow-up frontal gray matter disturbances detected with proton magnetic resonance spectroscopy
作者: Josefina Castro-FornielesNuria BargallóLuisa LázaroSusana AndrésCarles FalconMaria Teresa PlanaCarme Junqué
作者单位: 1Department of Child and Adolescent Psychiatry and Psychology, Institute Clinic of Neurosciences, Hospital Clínic Universitari of Barcelona, Villarroel 170, 08036 Barcelona, Spain
2Image Diagnostic Center, Hospital Clínic Universitari of Barcelona, Villarroel no. 170, 08036 Barcelona, Spain
3Department of Psychiatry and Clinical Psychobiology, Health Sciences Division, University of Barcelona, Casanova 143, 08036 Barcelona, Spain
4IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), Villarroel no.170, 08036 Barcelona, Spain
刊名: Journal of Psychiatric Research, 2006, Vol.41 (11), pp.952-958
来源数据库: Elsevier Journal
DOI: 10.1016/j.jpsychires.2006.09.013
关键词: Proton spectroscopyAnorexia nervosaAdolescentsFrontal gray-matterHormonal parameters
原始语种摘要: Abstract(#br)There are very few magnetic resonance spectroscopy studies in anorexia nervosa and none of them with young adolescent patients. We studied 12 anorexia nervosa (DSM-IV) patients aged 11–17 consecutively admitted to an Eating Disorders Unit. An evaluation with laboratory data, psychopathological scales, magnetic resonance spectroscopy ( 1 H MRS) and a neuropsychological battery was carried out at admission and after 7 months’ follow-up and weight recovery. Psychopathological and neuropsychological and MRS examinations were also performed in 12 control subjects. In the MRS study at the frontal gray matter, the anorexic group had a significantly lower N -acetyl-aspartate (NAA) ( p =.002), glutamate/glutamine (Glx) ( p ...
全文获取路径: Elsevier  (合作)
影响因子:4.066 (2012)

  • resonance 共振
  • spectroscopy 分光学
  • frontal 额骨
  • proton 质子
  • anorexia 食欲缺乏
  • magnetic 磁的
  • matter 物质
  • detected 找到
  • parameters 参数
  • follow